99% Apixaban CAS 503612-47-3

Nkọwa dị mkpirikpi:

Aha kemịkalụ:Apixaban
Aha ọzọ:1- (4-Methoxyphenyl) -7-oxo-6- (4- (2-oxopiperidin-1-yl) phenyl) -4,5,6,7-tetrahydro-1H-pyrazolo [3,4-c] pyridine -3-carboxaMide;1- (4-Methoxyphenyl) -7-oxo-6-[4- (2-oxopiperidin-1-yl) phenyl] -4,
5-dihydropyrazolo[3,4-c] pyridine-3-carboxaMide
Nọmba CAS:503612-47-3
Ịdị ọcha:99% nkeji
Usoro:C25H25N5O4
Ibu Molecular:459.50
Njirimara kemịkalụ:Apixaban bụ ọcha kristal ntụ ntụ.Ọ bụ ụdị ọhụrụ nke inhibitor Xa factor inhibitor, na aha azụmahịa ya bụ Eliquis.A na-eji Apixaban na-agwọ ndị ọrịa toro eto na-ahọrọ ịwa ahụ n'úkwù ma ọ bụ ikpere iji gbochie thromboembolism venous (VTE).

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ITEM	Ọkọlọtọ
Ọdịdị	Na-acha ọcha ruo na-acha ọcha siri ike
Ịdị ọcha	≥ 99%

Ngwa

Apixaban bụ ụdị ọhụrụ nke anticoagulant nke ọnụ, ụdị ọhụụ nke Xa inhibitor, nke a na-eji egbochi ma na-emeso mkpụkọ ọbara.
Apixaban bụ ihe mgbochi ọnụ ọhụrụ Xa inhibitor nke Bristol-Myers Squibb na Pfizer mebere.Site na igbochi ihe dị mkpa coagulation nke Xa, apixaban na-egbochi ọgbọ thrombin na thrombosis.

N'April 26, 2007, Bristol-Myers Squibb na Pfizer kwupụtara nkwalite nkwonkwo nke ọhụrụ apixaban anticoagulant nke Bristol-Myers Squibb nwere dị ka ihe nkwalite ọzọ na warfarin.
Na May 2011, apixaban bụ onye mbụ akwadoro maka igbochi thrombosis venous na ndị ọrịa toro eto na-ahọrọ ịwa ahụ n'úkwù ma ọ bụ ikpere na mba 27 EU, Iceland na Norway.
Na Nọvemba 20, 2012, European Commission kwadoro ELIQUIS (apixaban) maka igbochi ọrịa strok na usoro embolism na ndị toro eto na-enweghị valvular atrial fibrillation (NVAF) na otu ma ọ bụ karịa ihe ize ndụ.
Ụlọ ọrụ nri na ọgwụ ọjọọ nke Canada, Japan, na US Food and Drug Administration mechara kwadoro ELIQUIS (apixaban) maka igbochi ọrịa strok na usoro embolism na ndị okenye na-enweghị valvular atrial fibrillation (NVAF) na otu ma ọ bụ karịa ihe ize ndụ.
Na Eprel 12, 2013, ELIQUIS (Apixaban), kwupụtara ọkwa na ahịa na China.Apixaban bụ ihe na-egbochi ọnụ Xa inhibitor maka mgbochi nke thromboembolism venous (VTE) na ndị ọrịa toro eto na-ahọrọ ịwa ahụ ma ọ bụ ngbanwe ikpere.Mwepụta ya na-enye nhọrọ ọhụrụ dị mma ma dị irè maka mgbochi ọbara mgbe ịwa ahụ orthopedic na omume ụlọ ọgwụ, ma na-ebute ozi ọma nye ndị ọrịa China na-ahọrọ ngbanwe hip / ikpere.
Nnyocha ụlọ ọgwụ ekwenyela na e jiri ya tụnyere 40 mg subcutaneous injection of enoxaparin otu ugboro n'ụbọchị, 2.5 mg nke ELIQUIS (Apixaban) ọnụ ugboro abụọ n'ụbọchị bụ ihe dị irè karị n'igbochi venous thromboembolic omume mgbe hip ma ọ bụ ikpere dochie ịwa ahụ , na ọ dịghị eme ka ihe ize ndụ nke ọbara ọgbụgba.